Limited literature has focused on the use of totally tubeless mini-percutaneous nephrolithotomy (Mini-PCNL) for the treatment of large renal stones.

This Randomized Controlled trial aims to compare complication and safety of Mini-PCNL between total tubeless and tubeless Mini-PCNL.

After being informed about study and potential risks, all patient giving written informed consent with undergo a mini-PCNL operation. Patient who meet the eligibility requirements will be randomized in a single-blind manner (patient) in a 1:1 ratio to total tubeless mini-PCNL or tubeless mini-PCNL.

Inclusion Criteria:

• Patients diagnosed with kidney stones with a size ranging from 20 to 40 millimeters.
• Patients have undergone mini-PCNL, unilateral
• Absence of urinary tract infections before surgery.
• No urological congenital abnormality
• No coagulopathy

Exclusion Criteria:

• Presence of residual stones after the surgery, fragments larger than 4 millimeters.

• Patients with a single functioning kidney

• Complicated cases, including:

  1. massive bleeding in the upper tract during surgery
  2. Severe collecting systems injury during surgery
  3. Severe UPJ mucosa swelling considered unsafe by the physician, requiring the placement of a DJ stent or nephostomy tube

• Participants who decline or request withdrawal from the research study.

All eligible patients will be provided with an explanation of the research and invited to participate.

Patient will participate or not depends on whether they not meet the surgical exclusion criteria. If they meet the criteria, they will not participate in the research. If they not meet the criteria, they will be randomly assigned to one of the groups.

Patients will not be informed of the treatment intervention in advance