Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline

Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline

The goal of this clinical trial]is to evaluate if learning to play traditional board games could improve cognition in subjects with mild cognitive impairment and subjective cognitive decline. The main questions it aims to answer are:

• Do Go and Chess improve cognition?
• Is a game better than the other? Is the effect of both games on cognition synergistic?
• Do Go and Chess improve quality of life?
• Do Go and Chess improve mood?
• Do Go and Chess improve lifestyle?

Participants will be randomized to one of four groups:

• Group intervention with Go, once a week, for 12 weeks
• Group intervention with Chess, once a week, for 12 weeks
• Group intervention with Go and Chess, twice a week, for 12 weeks
• Control group

Inclusion Criteria:

• Diagnosis of mild cognitive impairment or subjective cognitive decline
• Willingness to participate in the board games classes
• Living within 20-minute driving distance from the center
• Signed informed consent

Exclusion Criteria:

• Prior knowledge of the the game rules (in case the subject knows one of the two, they can be randomized to the other one)
• Significant linguistic or sensory impairment (according to clinical judgment)
• Significant behavioral or psychiatric disturbances (according to clinical judgment)
• Significant medical comorbidities (according to clinical judgment)