Lumbar puncture (LP), often known as a "spinal tap," is a standard medical technique pioneered in the late 1900s by Heinrich Quincke. It involves the retrieval and analysis of cerebrospinal fluid (CSF) from the spinal cord, serving as the benchmark for diagnosing conditions like subarachnoid hemorrhage, meningitis, and specific neurological conditions. Pregabalin, an anticonvulsant medicine that blocks calcium entry, is used to treat a variety of diseases. It has been used to relieve pain in a variety of patient groups, including those with chronic pain, epilepsy, and anxiety disorders

Inclusion Criteria:

• age from 21 to 65 years old,
• both genders,
• confirmed diagnosis of postdural puncture headache (PDPH)

Exclusion Criteria:

• patient refusal
• known allergy to the drug used in the study
• patients with a history of convulsions
• chronic headaches
• contraindications to regional anesthesia (such as local infection and coagulation abnormalities).
• Clinical indications of elevated intracranial pressure or associated risk factors
• Deteriorated patients

Data will be shared upon reasonable request from corresponding author