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Carpal tunnel syndrome (CTS) is one of the most common peripheral nerve entrapment neuropathies, and it is characterized by pain, numbness, tingling, and weakness in the regions innervated by the median nerve (MN). CTS is believed to result from compression of the MN as it passes through the narrowed carpal tunnel with regard to gradual ischemia and fibrosis.Ultrasound-guided needle release of transverse carpal ligament(TCL) is an effective method to decompress the carpal.There are two main approaches to perform the release, short-axis or long-axis. However, there is no consensus about the optimal strategy.Thus, this study aimed to compare the efficacy of these two approaches for patients with mild-to-moderate CTS.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| long-axis group | Experimental | The patients in the long-axis group received one session of ultrasound-guided long-axis needle release of transverse carpal ligament. |
|
| short-axis group | Active Comparator | The patients in the short-axis group received one session of ultrasound-guided short-axis needle release of transverse carpal ligament. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| long-axis needle release | Other | The participants received one session of ultrasound-guided long-axis TCL needle release. |
|
| Measure | Description | Time Frame |
|---|---|---|
| visual analogue scale(VAS) scores | The VAS scores is the most common tool to assess the level of pain. Possible scores range from 0(no pain) to 10(worst possible pain). | Baseline as well as 1 month, 3 month and 6 months after injection. |
| Measure | Description | Time Frame |
|---|---|---|
| Boston carpal tunnel syndrome questionnaire(BCTQ) | BCTQ is the most commonly used evaluation for CTS symptoms; it contains two subscales: 11 items of symptom severity scale(SSS) and 8 items of functional status scale(FSS). Each item was scored 1-5 scores, with higher scores indicating greater severity and dysfunction. | Baseline as well as 1 month, 3 month and 6 months after injection. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jiaan Zhu, Dr | Peking University People's Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University People's Hospital | Beijing | Beijing Municipality | 100032 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28075090 | Background | Wipperman J, Goerl K. Carpal Tunnel Syndrome: Diagnosis and Management. Am Fam Physician. 2016 Dec 15;94(12):993-999. | |
| 34150584 | Background | Orhurhu V, Orman S, Peck J, Urits I, Orhurhu MS, Jones MR, Manchikanti L, Kaye AD, Odonkor C, Hirji S, Cornett EM, Imani F, Varrassi G, Viswanath O. Carpal Tunnel Release Surgery- A Systematic Review of Open and Endoscopic Approaches. Anesth Pain Med. 2020 Dec 26;10(6):e112291. doi: 10.5812/aapm.112291. eCollection 2020 Dec. |
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| ID | Term |
|---|---|
| D002349 | Carpal Tunnel Syndrome |
| ID | Term |
|---|---|
| D020423 | Median Neuropathy |
| D020422 | Mononeuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
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| short-axis needle release | Other | The participants received one session of ultrasound-guided long-axis TCL needle release. |
|
| cross-sectional area(CSA) of the median nerve | CSA of the median nerve under ultrasound guidance reflects the severity of the disease to some extent | Baseline as well as 1 month, 3 month and 6 months after injection. |
| 29154980 | Background | Petrover D, Richette P. Treatment of carpal tunnel syndrome : from ultrasonography to ultrasound guided carpal tunnel release. Joint Bone Spine. 2018 Oct;85(5):545-552. doi: 10.1016/j.jbspin.2017.11.003. Epub 2017 Nov 16. |
| D009422 | Nervous System Diseases |
| D009408 | Nerve Compression Syndromes |
| D012090 | Cumulative Trauma Disorders |
| D013180 | Sprains and Strains |
| D014947 | Wounds and Injuries |