At least one dose of L-arginie was administered in the early postoperative stage

No L-arginie was administered

Postoperative administration of L-Arginine hydrochloride before incidence of CS-AKI

Serum Creatinine Criteria:

Increase in Serum Creatinine:

An absolute increase in serum creatinine of 0.3 mg/dL (26.5 µmol/L) within 48 hours.

OR a percentage increase in serum creatinine of ≥50% within 7 days. These criteria are relative to the baseline creatinine level, which is usually the recent preadmission value.

Urine Output Criteria:

Oliguria, defined as a urine output <0.5 mL/kg/h for more than 6 hours. OR anuria, defined as a urine output <100 mL in 24 hours.

KDIGO defined AKI stage ≥ 2, or if dialysis is required for newly developed conditions

KDIGO classifies AKI into three stages based on the severity:

Stage 2:

Increase in serum creatinine of 2.0 to 2.9 times baseline OR Urine output <0.5 mL/kg/h for ≥12 hours.

Stage 3:

Increase in serum creatinine of 3.0 times baseline OR Increase in serum creatinine to ≥4.0 mg/dL OR Initiation of renal replacement therapy (RRT) OR Urine output <0.3 mL/kg/h for ≥24 hours OR anuria for ≥12 hours.