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The goal of this clinical trial is to test the impact of a medication-taking habit worksheet and discussion with a pharmacist in patients who are prescribed a new chronic medication for cardiovascular disease or depression. The main questions it aims to answer are:
The purpose of this study is to evaluate a habit adherence workup delivered by pharmacy in primary care. The study population will include patients taking new medications for chronic conditions like high blood pressure, high cholesterol, diabetes, and depression.
This study uses a sequential design which involves first evaluating 16 patients without the added habit worksheet, and then the second phase evaluates 16 patients with the habit worksheet. All participants meet with the pharmacist and are provided standard counseling on the new medications. All participants complete the pre and post survey.
The pharmacist will be trained on the medication habit workup worksheet which has the patient choose cues they will use to develop their medication-taking habit. These will include associating the new habit with hygiene habits like toothbrushing, other habits like making coffee or eating breakfast, or visual cues like setting medications out where they will be easily noticed when doing other habits like getting dressed. Patients will take their sheet with them as a reminder of their plan. Patients also will receive medication counseling. The encounters will occur in a private clinic room.
All participants will complete baseline and follow-up surveys, which will include space for open-ended comments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard of care | Active Comparator | The first 16 patients will receive standard medication counseling from the pharmacist |
|
| Habit workup arm | Experimental | The second 16 patients will receive the habit workup in addition to medication counseling |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Habit workup | Behavioral | The patient and pharmacist will work together to specify a cue to help them take their medicine every day (e.g. brushing teeth, getting dressed, eating breakfast, making coffee, alarms, visual reminders etc). |
| Measure | Description | Time Frame |
|---|---|---|
| Medication Adherence Report Scale | Five-items from the medication Adherence Report scale assessed using 5-point Likert scale. Possible range 5-25 (higher values associated with greater medication adherence) | From enrollment to 100 days following |
| 4-item Habit Automaticity Index | This 4 scale uses four validated items from the Habit Automaticity Index and uses a 5-point Likert scale. Possible range 4-20 (higher values associated with greater automaticity of medication-taking habit) | From enrollment to 100 days following |
| Measure | Description | Time Frame |
|---|---|---|
| Beliefs about Medicines Questionnaire | For this study,, 5 items specific, 5 items general from the beliefs about Medicines questionnaire by Horne. Possible range 5-25 for each scale. (for the specific beliefs, lower values are associated with more positive medication beliefs, with the general, higher numbers are associated with greater medication beliefs) | From enrollment to 100 days following |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cedar Valley Primary Care & Walk-In Clinic | Waterloo IA | Waterloo | Iowa | 50701 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40946014 | Derived | Witry M, Hoehns J, Phillips LA. Pilot of a pharmacist-delivered habit-based intervention to support medication adherence in primary care. Res Social Adm Pharm. 2026 Jan;22(1):147-151. doi: 10.1016/j.sapharm.2025.09.003. Epub 2025 Sep 6. |
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Data on primary and secondary outcomes, and basic demographic information
1 year following the close of the study.
They can email the principle investigator
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| ID | Term |
|---|---|
| D055118 | Medication Adherence |
| D006184 | Habits |
| ID | Term |
|---|---|
| D010349 | Patient Compliance |
| D010342 | Patient Acceptance of Health Care |
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
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| Standard Medication Counseling | Behavioral | The pharmacist provides standard counseling on the new medication |
|
| D001519 | Behavior |