Association Between Handgrip Strength and Small Airway Disease in Patients with Stable Chronic Obstructive Pulmonary Disease

Association Between Handgrip Strength and Small Airway Disease in Patients with Stable Chronic Obstructive Pulmonary Disease

The goal of this observational study is to investigate the correlation between handgrip strength and small airway disease among patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:

• Is handgrip strength correlated with small airway disease in COPD patients? Participants will perform handgrip strength test and impulse oscillometry (IOS).

This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and impulse oscillometry will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Small airway disease will be assessed using IOS.

Inclusion Criteria:

• COPD patients aged 40 years or older
• Confirmed diagnosis by spirometry (post-bronchodilator FEV1/FVC <0.7)
• Smoking history 10 pack-years or more

Exclusion Criteria:

• COPD exacerbation within 3 months
• Inability to perform handgrip strength test or impulse oscillometry