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The goal of this observational study is to investigate the relationship between handgrip strength and air trapping in patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:
• Is handgrip strength correlated with air trapping in COPD patients? Participants will perform handgrip strength test and lung volume measurement.
This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and lung volume measurement will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Lung volume will be assessed using a body plethysmograph.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COPD | COPD patients aged 40 years or older with a postbronchodilator ratio of forced expiratory volume at one second (FEV1) to forced vital capacity (FVC) <0.7. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Handgrip strength | Diagnostic Test | Handgrip strength will be measured by 3 efforts. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between handgrip strength and air trapping in COPD patients | This correlation will be reported as correlation coefficient (R). | At day 1 of the study |
| Measure | Description | Time Frame |
|---|---|---|
| The best cutoff value of handgrip strength for predicting air trapping in COPD patients | The best cutoff value will be determined by the area under the Receiver Operator Characteristic curve (ROC). | At day 1 of the study |
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Inclusion Criteria:
Exclusion Criteria:
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COPD patients aged 40 years or older who are confirmed diagnosis by spirometry (postbronchodilator FEV1/FVC <0.7) and smoking history 10 pack-years or more.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Thammasat University Faculty of Medicine | Pathum Thani | Changwat Pathum Thani | 12120 | Thailand |
Individual patient data (IPD) and documents will be available for sharing immediately after publication for a period of 2 years.
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |