The Prognostic Impact of Right Ventricular Systolic Dysfunction on the Survival of Patients With Sepsis and Septic Shock

The Prognostic Impact of Right Ventricular Systolic Dysfunction on the Survival of Patients With Sepsis and Septic Shock

This study sought to evaluate the association of right ventricular systolic dysfunction and 28-day in-hospital mortality in patients with sepsis and septic shock. Prospective cohort study of adult patients admitted at Burapha university hospital from October 1, 2022 through June 30, 2023 for sepsis and septic shock, who had an echocardiogram within 72 hours after admission for evaluating right ventricular systolic function. Right ventricular systolic dysfunction was defned by the American Society of Echocardiography criteria. Outcomes included 28-day in-hospital mortality, maximal blood lactate, length of intensive care unit(ICU) stay and duration of mechanical ventilation.

Inclusion Criteria:

• aged 18 years or older
• diagnosed with sepsis or septic shock according to Sepsis-3 criteria
• received an echocardiogram within 72 hours after admission

Exclusion Criteria:

• prior diagnosis of pulmonary hypertension,
• cor-pulmonale,
• significant valvular heart disease,
• acute coronary syndrome,
• aortic dissection,
• heart failure
• inability to follow up within 28 days