Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The goal of this clinical randomized trial is to test whether an integrated care involving peripheral functional magnetic stimulation and nutritional supplement is beneficial in population with age-related sarcopenia, as compared to usual care.
We will recruit participants with sarcopenia or possible sarcopenia. The participants will be divided into 2 groups. One group, the "integrated care" group, will receive both the peripheral functional magnetic stimulation to both the upper and lower limbs and nutritional supplement for consecutive 8 weeks. The other group, the "usual care" group, will receive an educational digital versatile disc (DVD) and a handbook for exercise suggestions on sarcopenia. We will compare before and after the intervention about the body composition, handgrip strength, 5-time chair stand test, 6-meter walk, and blood test for C-reactive protein and other cytokines related to sarcopenia. The participant's nutritional condition, activity level, life quality will also be analyzed via questionnaires before and after the intervention.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Integrated care | Experimental | Participants in this group will receive both the peripheral functional magnetic stimulation to both the upper and lower limbs and nutritional supplement for consecutive 8 weeks. |
|
| Usual care | Active Comparator | Participants in this group will receive an educational DVD and one session of oral instructions on general care and exercise suggestions for sarcopenia. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Peripheral functional magnetic stimulation (ISKRA MEDICAL TESLA Former prestige Magneto therapy) | Device | The peripheral functional magnetic stimulation will be conducted 30 minutes a session, 2 sessions per week, for consecutive 8 weeks. The stimulation will be placed over bilateral forearm flexor muscles and bilateral thighs over rectus femoris muscles. |
| Measure | Description | Time Frame |
|---|---|---|
| Body composition | We use dual energy x-ray absorptiometry to evaluate the muscle mass (kg/m2) in the subjects. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| Handgrip strength | We use a dynamometer to measure the handgrip strength (kg) | Before the intervention, and 1-2 weeks after the 8-week intervention |
| 5-time chair stand test | We measure the time of a subject to transfer from a seated to a standing position and back to sitting five times. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| 6-meter walk | We measure the time of a subject to walk with the usual speed straightly for 6 meters. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Leg circumference | We measure the largest calf circumference with seated position with knee flexed in 90 degrees. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| Cytokines related to sarcopenia |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shao-Yu Chi | Contact | +886972653975 | shaoyuchi.tw@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Shao-Yu Chi | National Taiwan University Hospital Beihu Branch | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Taiwan University Hospital Bei-Hu Branch | Taipei | Taiwan |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Nutritional supplementation (ENSURE HIGH CALCIUM) | Dietary Supplement | The nutritional supplementation includes 7 cans of "ENSURE HIGH CALCIUM" per week for 8 consecutive weeks. |
|
| Education | Behavioral | The education includes a DVD and one session of oral instructions on general care and exercise suggestions for sarcopenia. |
|
We will check the concentrations of cytokines including the c-reactive protein from our subjects.
| Before the intervention, and 1-2 weeks after the 8-week intervention |
| Nutritional status | We use the questionnaire Mini Nutritional Assessment to evaluate the subjects' nutritional status. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| Activity level | We use the International Physical Activity Questionnaire to evaluate the subjects' activity levels. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| Life quality | We use the EuroQol-5 dimensions (EQ-5D) and Taiwan Short Form-36 questionnaires to evaluate the subjects' health life quality. | Before the intervention, and 1-2 weeks after the 8-week intervention |
| ID | Term |
|---|---|
| D055948 | Sarcopenia |
| ID | Term |
|---|---|
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
Not provided
Not provided
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D004522 | Educational Status |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
| D012959 | Socioeconomic Factors |
| D011154 | Population Characteristics |
Not provided
Not provided