The purpose of this study is to assess the impact of a combined exercise-nutrition intervention in primary clinics on sarcopenia indices, physical function, and quality of life in community-dwelling older adults with possible sarcopenia.

This study will investigate the effects of a 12-week combined exercise-nutrition intervention by comparing it with a control group receiving standard care (usual care) by assessing the sarcopenia indicators, functional recovery, and individual satisfaction. This is an interventional clinical study designed to recruit subjects, analyze data, identify problems, find improvement areas, and explore potential solutions.

Inclusion Criteria:

• 65 to 85 years of age

• Men and women with possible sarcopenia

  • If included in the possible sarcopenia criteria in the 2019 Asian Working Group for Sarcopenia(AWGS) criteria A Simple Questionnaire to Rapidly Diagnose Sarcopenia(The Korean SARC-F questionnaire) score is 4 or higher; or Calf circumference (Men's: <34 cm, Women's: <33 cm) + Decreased muscle strength (male: <28kg, female: <18kg) or Decreased physical function (if it takes more than 12 seconds from the 5-chair stand test)
  • [(1) and {(2) or (3)}]

Exclusion Criteria:

• Renal failure: Serum creatine exceeding 2.0 mg/dl
• Uncontrolled hypertension: systolic/diastolic blood pressure greater than 150/90 millimeter of mercury(mmHg)
• Uncontrolled diabetes: glycated hemoglobin (HbA1C) over 7.5%
• Subject who are receiving treatment (steroids, anticancer drugs, etc.) that can affect muscle mass
• Subjects with myocardial infarction or angina pectoris, stroke disease
• Malignant tumor: Subject who has a history of cancer within 5 years or is currently receiving treatment
• Subjects who have liver cirrhosis and uncontrolled hepatitis (Aspartate aminotransferase or Alanine aminotransferase is more than three times the upper limit of the reference range)
• Subjects who have chronic diseases such as musculoskeletal disorders that are impossible to exercise
• Subjects who are allergic to soybeans, coix, and brown rice

Research information will be provided to third parties (data processing organizations, academic societies, etc.) and used for secondary research. Individual participant data will be stored and used for 5 years after completion of the primary study. When used for secondary research, it will be used after deliberation by the institutional committee, and all information provided will be used only to create statistics for research purposes.

The purpose and expected effect of third-party provision of research information and use of secondary research is to contribute to the promotion of national health.

Personal information to be collected: Personal identification information (date of birth, name, gender, etc.), personal information (medical records necessary to determine the purpose of this study)

It will be distributed for storage/management/connection/provision for 5 years from the end of primary research by a data management agency determined by the Minister of Health and Welfare, and will be provided upon request by researchers for secondary research use only within that period.

After deliberation by the institutional committee, it will be provided and utilized only for research that is judged to be of public interest through the Data Provision Deliberation Committee*.

*Formation of a future data provision deliberation committee