Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Netherlands Organisation for Scientific Research | OTHER_GOV |
Not provided
Not provided
Not provided
Objective: To evaluate the technical performance of a novel cascaded wave imaging technique compared to plane wave imaging for blood flow imaging in patients with and without carotid artery stenosis.
Study design: Observational, feasibility study in a total of 10 patients with and 10 patients without a hemodynamic significant carotid artery plaque.
Intervention (observational): all participants will undergo a carotid ultrasound measurement including conventional duplex ultrasound and ultrasound based flow imaging using plane waves and cascaded waves.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants with a hemodynamic significant carotid artery stenosis |
| ||
| Participants without a hemodynamic significant carotid artery stenosis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Conventional duplex | Diagnostic Test | Conventional carotid duplex measurement |
|
| Measure | Description | Time Frame |
|---|---|---|
| 2D velocity vector fields obtained by plane wave and cascaded wave imaging of the carotid artery | After study completion, average of one year |
| Measure | Description | Time Frame |
|---|---|---|
| Signal-to-noise ratio obtained from plane wave and cascaded wave imaging will be obtained and compared for different vessel depths | After study completion, average of one year | |
| Cross-correlation maps of plane wave and cascaded wave imaging will be obtained and compared for different vessel depths |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
10 patients with and 10 patients without a hemodynamic significant carotid artery stenosis
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Radboud university medical center | Nijmegen | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41217908 | Derived | de Bakker JMK, Ruisch J, de Korte CL, Saris AECM. Cascaded Plane Wave Ultrasound Velocity Vector Imaging: In Vivo Feasibility in Carotid Arteries. IEEE Trans Ultrason Ferroelectr Freq Control. 2025 Dec;72(12):1607-1617. doi: 10.1109/TUFFC.2025.3631658. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Ultrasound-based flow imaging using plane wave imaging | Diagnostic Test | Ultrasound-based flow imaging using plane wave imaging |
|
| Ultrasound-based flow imaging using cascaded wave imaging | Diagnostic Test | Ultrasound-based flow imaging using cascaded wave imaging |
|
| After study completion, average of one year |
| Velocity vector fields obtained from plane wave and cascaded wave imaging will be obtained and compared | After study completion, average of one year |
| Blood-flow related parameters, including vector complexity and vorticity, will be calculated from 2D velocity fields. | After study completion, average of one year |
| Spatiotemporal blood flow profiles obtained with plane wave, cascaded wave and conventional duplex ultrasound will be compared to assess the correlation between these techniques | After study completion, average of one year |
| ID | Term |
|---|---|
| D016893 | Carotid Stenosis |
| ID | Term |
|---|---|
| D002340 | Carotid Artery Diseases |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided