Clinical Evaluation of an Experimental Remineralization Product

Clinical Study of Tooth Enamel Remineralization Using DoReMin Product

The study is designed as a split-mouth randomised controlled study. This means within the mouth of one patient one tooth with an initial lesion is treated and coated with the Experimental Remineralization product whereas another comparable tooth with an initial lesion is left untreated. Patients are included upon meeting the inclusion criteria as defined for this clinical trial. In the test group, a remineralization of the incipient carious lesion is expected. The patients are recalled after 1 day (optional), 4 weeks, 4 months and finally after 1 year to evaluate the untreated and treated lesion.

Inclusion Criteria:

• At least two incipient carious lesions on the buccal or oral surface of a permanent tooth. Neighbouring teeth should not be in two different groups. There is no maximum amount of lesions.
• Active caries lesion
• Patient at risk of caries
• Vital teeth

Exclusion Criteria:

• Pregnancy
• Enamel detachment at the site of investigation
• Allergies (DoReMin)
• Chronic diseases