This is an observational study to address the important knowledge gap of the metabolic and inflammatory impact of acute overeating and whether timing of acute overeating may modify these effects. The hypothesis is that acute overconsumption of calories will promote inflammation and metabolic dysfunction, with the most detrimental effects observed with evening caloric overconsumption. The expectation is that this study to provide critical insights into the biological consequences of overeating, which will direct novel approaches combating overeating and its detrimental health effects.

Inclusion Criteria:

• ages of 18-65 years old
• not pregnant
• no comorbid conditions
• normal BMI (18.5 - 24.9 kg/m2)
• Weight ≥120 lbs self-reported weight

Exclusion Criteria:

• N/A