Time-restricted Feeding and Health

The Effect of Early Time-restricted Feeding in Metabolic Health - Differences Between Chronotypes.

The purpose of this pilot, single-arm clinical trial is to assess the effects of time-restricted feeding on overall health, including body composition, glycemic and lipidemic profile, as well as appetite-regulating hormones, including glucagon-like peptides 1(GLP-1) oxyntomodulin, glucagon. Additionally, the study aims to evaluate the impact of this dietary pattern on circadian rhythm parameters, including acrophase, mesor, and amplitude.

Inclusion Criteria:

• Healthy men or women aged 18-35 years
• Habitual daily eating window >10 hours
• Stable body weight over the past 3 months (< ±10% change)
• Able to provide informed consent independently

Exclusion Criteria:

• Night shift work more than once per week
• Presence of chronic diseases (e.g., cancer, renal or hepatic disease, inflammatory bowel disease, hypertension, diabetes, cognitive or psychiatric disorders)
• Eating disorders
• Use of medications affecting the intervention (e.g., corticosteroids, antidiabetics)
• Pregnancy or planning pregnancy within the next 12 months
• Diagnosis of insomnia