Feasibility and Effectiveness of tDCS in the Treatment of Post-stroke Fatigue (EFECTS).

Feasibility and Effectiveness of Tdcs in a Multimodal Treatment With Health Education and Aerobic Exercise in the Treatment of Post-stroke Fatigue.

This study aims to analyze the use of non-invasive brain stimulation (tDCS) is beneficial for the treatment of post-stroke fatigue.

A single-blind randomized clinical trial will be conducted. The intervention will consist of 8 20-minute tDCS sessions conducted over four weeks. The stimulation will be performed by applying the stimulation to the dorsolateral prefrontal cortex on the left side (F3) and the cathode will be at point O2 of the right hemisphere. The study will consist of two groups: the control group in which sham stimulation will be applied and therapeutic education and aerobic exercise; the intervention group in which stimulation, therapeutic education and therapeutic exercise will be carried out.

Inclusion Criteria:

• First stroke within 45 (+-7) days of the ischemic or hemorrhagic episode.
• Ability to understand and execute simple instructions
• Over 18 years.
• Fatigue Scale of fatigue severity with a score greater than or equal to 24

Exclusion Criteria:

• A score > 2 on the modified Rankin Scale (mRS) before the stroke.
• Patients with decompensated cardiorespiratory and/or psychiatric pathology.
• Comorbidity causing disproportionate fatigue, such as long-term COVID.
• Patients who are cancer survivors or who are undergoing cancer treatment.
• Patients with a history of epilepsy or who are taking antiepileptic medication.
• Patents with major depression.