A Multi-omics-based Metabolic Typing Study of Gastric Cancer

Clinical Study on Metabolic Typing of Gastric Cancer Based on Transcriptome, Metabolome and Other Multi-omics

In the study, the investigators obtained gastric cancer tissues from 480 gastric cancer patients who had undergone surgery at the Zhejiang Cancer Hospital's biospecimen bank between 2012-2019, and obtained relevant clinical information. The gastric cancer tissues were subjected to transcriptomic, metabolomic and other multi-omics testing, and analyzed for the metabolic changes of gastric cancer, and proposed to discover relevant therapeutic targets.

Inclusion Criteria:

• 18≤age≤80
• Histologically or cytologically confirmed gastric cancer
• Undergo surgery for radical or palliative gastric cancer (both open and laparoscopic)
• Patients with survival follow-up information

Exclusion Criteria:

• Two or more kinds of malignant tumors at the same time
• Incomplete or missing case information
• Preoperative diagnosis of residual gastric cancer