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The use of low dose aspirin is recommended for high risk patients to reduce the risk of pre-eclampsia, placental abruption and antepartum hemorrhage. Recent studies have shown that in a specific population, the use of low dose aspirin might reduce the risk of preterm birth in pregnant women with singleton pregnancy. In June 2022, clinique ovo started implementing the use of Aspirin 162 mg instead of 81 mg in the frozen embryo transfer cycles based on recent study outcomes. The use of Aspirin 162 mg might have additional benefits on the embryo transfer outcomes by decreasing the miscarriage. Moreover this can be continued until late in pregnancy without adverse effects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Aspirin 81 mg for Frozen Embryo Transfer (FET) | Subjects were prescribed Aspirin 81 mg to be started on the third day of their menstrual cycle in preparation for their FET. |
| |
| Aspirin 162 mg for Frozen Embryo Transfer (FET) | Subjects were prescribed Aspirin 162 mg to be started on the third day of their menstrual cycle in preparation for their FET |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Frozen embryo transfer | Other | A frozen embryo transfer involves thawing a fertilized embryo and transferring it in the uterus in order to obtain a pregnancy |
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| Measure | Description | Time Frame |
|---|---|---|
| Compare clinical pregnancy rate between patients prescribed Aspirin 81 mg vs Aspirin 162 mg | clinical pregnancy is the presence of fetal heartbeat at the viability ultrasound | Time Frame: 6 to 8 weeks after Frozen Embryo Transfer |
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Inclusion Criteria:
Exclusion Criteria:
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Women able to have an embryo transfered in their uterus
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FET Data spreadsheet from January 2022 to December 2022
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| Name | Affiliation | Role |
|---|---|---|
| Wael Jamal, MD | Clinique Ovo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinique Ovo | Montreal | Quebec | H4P 2S4 | Canada |
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