To date, the underlying causes of community-acquired fever, particularly non-malarial fever, are insufficiently documented in Guinea. Moreover, diagnostic capacity is limited, leading to inadequate prescription of antibiotics and antimalarials, as well as substantial delay in outbreak recognition. Thus, the investigators undertook a prospective observational multi-centric cohort study of febrile patients presenting at the emergency and outpatient department of selected health centers, districts and regional hospitals in four ecologically distinct sentinel health districts in Guinea.

Inclusion Criteria:

• Age ≥2 months old
• Documented fever (axillary temperature >37.5°C) at presentation or fever reported within the prior 24 hours
• Availability for follow-up for 21 days
• Willingness and ability of the patient or culturally acceptable representative to give informed consent for participation in the study

Exclusion Criteria:

• History of hospitalization (for > 48 hours within the last 14 days) at any health facility

Febrile patients presenting with documented fever (> 37.5°C, axillary temperature) or reporting fever within the prior 24 hours (≤37.5°C, axillary temperature) at the emergency or outpatient department of the selected health facilities.

This is under development and will be filled when finalized.

Yet to be finalized.

Yet to be finalized. However, investigators are opened to collaborate on that data that will be generated.