Cardiogenic Acute Pulmonary Edema in Subjects Over 75 Years Old: Impact of Non-invasive Ventilation on Mortality

Cardiogenic Acute Pulmonary Edema in Subjects Over 75 Years Old: Impact of Non-invasive Ventilation on Mortality

People aged over 75 represent almost 10% of the general population, and 12 to 14% of patients consulting emergency departments. Cardiogenic acute pulmonary edema (APO) is a very common reason for admission to the emergency room. The effectiveness of non-invasive ventilation (NIV) has been demonstrated during the management of PAO and would allow, compared to medical treatment alone, a more rapid improvement in clinical and gasometric parameters as well as a reduction in the need for ventilation. orotracheal intubation. On the other hand, the impact of NIV on mortality in cardiogenic PAO seems poorly defined, with lower levels of scientific evidence regarding a possible benefit in terms of survival, particularly in the elderly population.

The objective of this study is to determine whether the use of NIV in cardiogenic PAO in elderly subjects admitted to the emergency room of Strasbourg University Hospital would have an impact in terms of mortality up to 6 months compared to medical treatment alone.

Inclusion Criteria:

• Adult subject (> 75 years old)
• Admission to the NHC emergency room between January 1, 2021 and October 31, 2021
• Diagnosis of cardiogenic PAO
• Indication of NIV according to current recommendations
• Subject not opposing the reuse of their data for scientific research purposes.

Exclusion Criteria:

• Subject having expressed his opposition to the reuse of his data for scientific research purposes.
• Presence of an absolute contraindication to NIV
• Respiratory distress due to pneumonia or other diagnosis
• RT-PCR Sars Cov 2 positive in emergency