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This is a clinical trial from the Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1020. The goal of this clinical trial is to confirm the therapeutic effect of Wedge resection for ground-glass opacity-featured lung cancer with a size less than 2cm and a consolidation-to-tumor ratio between 0.25 to 0.5.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Wedge resection | Experimental | Wedge resection is performed for early-stage lung cancer to remove a wedge-shaped section of lung tissue. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Wedge resection | Procedure | Wedge resection is a surgical procedure that is done to remove a wedge-shaped section of lung tissue, usually for treating lung cancer. A wedge resection is less invasive than some of the other surgical options used to remove lung cancer. |
| Measure | Description | Time Frame |
|---|---|---|
| 5-year overall survival | The event is defined as the death due to any causes. | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| 5-year recurrence-free survival | The event is defined as the tumor recurrence. | 5 years |
| Postoperative lung function (FEV1) | forced expiratory volume in one second (FEV1) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tong Li | Contact | +86 18813039287 | litong_medical@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fudan University Shanghai Cancer Center | Shanghai | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39144343 | Derived | Li T, Fu F, Zhang Y, Chen H. Protocol for a single-arm, multicenter, prospective, confirmatory phase III trial of wedge resection for invasive ground glass opacity-featured lung cancer with a size </=2 cm and a consolidation tumor ratio between 0.25 and 0.5 (ECTOP-1020 study). J Thorac Dis. 2024 Jul 30;16(7):4711-4718. doi: 10.21037/jtd-24-440. Epub 2024 Jul 9. |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| 5 years |
| Postoperative lung function | forced vital capacity (FVC) | 5 years |
| Sites of tumor recurrence and metastasis | 5 years |
| Radical wedge resection (R0 resection) completion rate | 5 years |
| Surgery-related complications | 5 years |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |