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This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1025. The goal of this clinical trial is to confirm the theraputic effect of segmentectomy for solid-dominant invasive lung cancer with size of 2-3cm. The main questions it aims to answer are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Segmentectomy | Experimental | Segmentectomy is performed for solid-dominant invasive lung cancer with size of 2-3cm. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Segmentectomy | Procedure | The lungs are divided into multiple lobes. A segmentectomy involves the removal of part of one of the lobes of the lung to entirely remove a cancerous tumor. segmentectomy can preserve more normal functional lung tissues. |
| Measure | Description | Time Frame |
|---|---|---|
| 5-year disease-free survival | The event is defined as the tumor recurrence or the death due to any causes. | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Lung function test | FEV1/FVC ratio | Half year and one year after surgical resection |
| 5-year overall survival | The event is defined as death due to any causes or last follow-up. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fangqiu Fu, M.D. | Contact | +86-13122677592 | fufangqiu12@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Haiquan Chen, M.D. | Fudan University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fudan University Shanghai Cancer Center | Recruiting | Shanghai | Shanghai Municipality | China |
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| ID | Term |
|---|---|
| D000077192 | Adenocarcinoma of Lung |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| ID | Term |
|---|---|
| D015412 | Mastectomy, Segmental |
| ID | Term |
|---|---|
| D008408 | Mastectomy |
| D013514 | Surgical Procedures, Operative |
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|
| 5 years |
| The site of tumor recurrence and metastasis | Outpatient follow-up was conducted regularly after surgery, and the recurrence or metastasis site and time will be recorded. | From date of surgery to the last follow-up or date of death from any cause, whichever came first, assessed up to 5 years. |
| Segmentectomy completion rate | Proportion of patients who complete planned segmentectomy. | From the beginning of the surgery to the end of the surgery. |
| Radical segmentectomy (R0 resection) completion rate | According to the postoperative pathology report of the patients, the proportion of patients with no residual tumor after radical segmentectomy accounted for all patients who underwent segmentectomy. | From surgery to the release of the final pathology report, an average of two weeks. |
| Surgery-related complications | such as air leak, atrial fibrillation, intraoperative or postoperative hemorrhage, postoperative infection, bronchopleural fistula, etc | From surgery to patient discharge or 30 days after surgery. |
| D009369 | Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |