Genetic Factors and CP Pregnancy Outcomes

The Impact of Genetic Factors on Pregnancy Outcomes in Chronic Pancreatitis

To explore the impact of chronic pancreatitis (CP) susceptibility genes on pregnancy outcomes.

The goal of this observational study is to explore the impact of CP susceptibility genes (SPINK1, PRSS1, CTRC, CFTR) on pregnancy outcomes (including both maternal and fetal outcomes) in a large Chinese cohort. Participants will be asked to provide their pregnancy-related data.

Inclusion Criteria:

• female patients with a diagnosis of chronic pancreatitis
• have known genetic backgrounds and pregnancy history
• agree to join the study and provide informed consent

Exclusion Criteria:

• patients without documented pregnancy
• patients who denied to provide pregnancy-related information, or with incomplete pregnancy characteristics and/or outcomes
• patients with other autoimmune comorbidities that might influence pregnancy outcomes, such as systemic lupus erythematosus, autoimmune thyroid diseases, etc