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The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy(DPN).
This is a multicenter study(approximately four) with over 1000 subjects.Clinical data were collected by consulting the patient's electronic history. The data included demographic information, blood biochemical markers and electromyography. All participants provided their written informed consent to participate in this study.The study protocol was approved by the Ethics Committee of the First Affiliated Hospital of Wenzhou Medical University(KY-2022-R009).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DPN group | Patients with type 2 diabetic peripheral neuropathy were categorized into the DPN group | ||
| Diabetic group | patients with type 2 diabetes mellitus but not with DPN were distributed into the Diabetic group. | ||
| control group | The other individuals without type 2 diabetes mellitus were selected as the control group |
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| Measure | Description | Time Frame |
|---|---|---|
| the severity of DPN | The nerve conduction examination was conducted at a room temperature of 24℃, with the legs warmed using an electric heating pad for at least 10 minutes to achieve a skin temperature of 32-35℃. The nerve conduction velocities and nerve conduction amplitudes were measured for both sides of the upper and lower limbs, including motor and sensory branches of the median nerve; motor and sensory branches of the ulnar nerve; motor branch of peroneal nerve; motor branch of the tibial nerve; sensory branch of the superficial peroneal nerve. In addition, both sides of the tibial nerve F-wave were recorded, and the lower one was regarded as the final F-wave. Slowed/blocked nerve conduction was defined as more than 2.5 standard deviation below the control nerve conduction threshold. Nerve conduction is defined as abnormal when two or more nerve abnormalities are detected. | From admission to discharge, up to 1 week |
| the presence of DPN | When any of the elements of the screening process -- symptoms, signs, or abnormal nerve conduction parameters --was abnormal, medical records would be scrutinized to see if these participants had accepted a previous DPN diagnosis by a specialist. | From admission to discharge, up to 1 week |
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Inclusion Criteria:
Exclusion Criteria:
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This is a multicenter study(approximately four) with over 1000 subjects.Clinical data were collected by consulting the patient's electronic history. The data included demographic information, blood biochemical markers and electromyography. All participants provided their written informed consent to participate in this study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Binbin Deng | Contact | dbinbin@aliyun.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| First Affiliated Hospital of Wenzhou Medical University | Recruiting | Wenzhou | Zhejiang | 325000 | China |
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