The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy

The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy

The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy.

This is a multi-center(about five), randomized, double-blind, placebo-controlled clinical trial with over 1000 subjects.Clinical data were collected by consulting the patient's electronic history. The data included demographic information, blood biochemical markers and electromyography. All participants provided their written informed consent to participate in this study.The study protocol was approved by the Ethics Committee of the First Affiliated Hospital of Wenzhou Medical University(KY-2022-R009).

Inclusion Criteria:

• patients who had undergone nerve conduction examination by electromyography(EMG).

Exclusion Criteria:

• pregnancy and lactation; chronic liver disease, kidney disease, arrhythmias, malignant diseases, severe respiratory diseases, heart failure, and acute infections;
• patients with alcohol abuse; history of Autoimmune liver disease, liver disease or abnormal liver function at baseline;
• parathyroid diseases (including hyperthyroidism and hypothyroidism);
• pancreatitis, pancreatectomy or any transplant;
• patients with malignancy and any serious concomitant disease limit the existence of life expectancy