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The investigators are examining the impact of an 8-week multi-modal exercise program (resistance and cardiovascular training) delivered 2 times per week on physical function adults (>18 years old) with cancer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise | Experimental | 2 days/week of resistance and cardiovascular exercise for 8-weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Behavioral | A combination of resistance exercise and cardiovascular exercise (performed 2 days per week for 8-weeks) is tailored to each individual in accordance with their medical/cancer-related history, baseline assessments of physical function, and overall goals. Resistance exercise includes 6-8 exercises targeting major muscle groups. The first week of the program is used to familiarize participants to the exercises of the program, provide coaching on safe and appropriate technique, and identifying initial load for 2 sets of 12 repetitions (equivalent to ~65% 1 repetition maximum), with a goal of working towards 4 sets of 8 reps. Additionally, participants are asked to perform 20-30 minutes of moderate-to-vigorous aerobic activity (approximately 60-85% age-predicted heart rate maximum) via walking, jogging, or cycling each session. |
| Measure | Description | Time Frame |
|---|---|---|
| Bellarmine Norton Assessment Tool (2-minute Step Test) | 2-minute Step Test: Number of times an individuals' knee reaches a predetermined heigh during a 2-minute period of marching | 0 and 8-weeks |
| Bellarmine Norton Assessment Tool (Timed Arm Curl) | Timed Arm Curl: Number of repetitions an arm curl individuals can complete in 30 seconds) | 0 and 8-weeks |
| Bellarmine Norton Assessment Tool (30 second Chair Stand) | Chair Stand: Number of times participants can stand from a sitting position and return to sitting in 30 seconds | 0 and 8-weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Fatigue | The Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue Scale: The FACIT-Fatigue scale is a 13-item scale that will be used to assess cancer-related fatigue. The FACIT-Fatigue scale is scored on a 0-4 response scale from 0 = "not at all" to 4 "very much", regarding items related to fatigue and energy in the past 7 days. Lower score indicates greater fatigue | 0 and 8-weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of South Carolina | Columbia | South Carolina | 29205 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42026875 | Derived | Bottone GL, Anderson KS, Brooks AM, Harrington SE, Nakfoor B, Jackson KE, Scott BM, Fairman CM. Evaluating the Test-Retest Reliability and Measurement Error of a Sit-Stand-Power Test in Individuals Treated for Cancer. Integr Cancer Ther. 2026 Jan-Dec;25:15347354261442462. doi: 10.1177/15347354261442462. Epub 2026 Apr 23. | |
| 39478564 |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Fairman CM, Harrington SE, Schumpp AR, Brooks AM, Jones MJ, Kim J, Kennedy MA. Planning and evaluating an integrated clinical exercise oncology service: an exploratory mixed-methods study. BMC Health Serv Res. 2024 Oct 31;24(1):1318. doi: 10.1186/s12913-024-11797-0. |