Curcumin Gel On Radiation Induced Oral Mucositis

The Effect of Curcuma Long Oral Gel in Relation to Salivary Epidermal Growth Factor & Interleukin-8 on Radiation Induced Oral Mucositis in Iraqi Cancer Patients

The goal of this clinical study is to investigate the effect of a curcuma longa oral gel (curenext) on reducing radiation-induced oral mucositis severity in cancer patients and provide a context for understanding if there is a relationship between the curcumin clinical effect and production of EGFs and IL8.

Researchers will compare between curcumin group and standard treatment group.

Inclusion Criteria:

• Patients above 16 years having histopathologically confirmed cancer in head and neck region who planned to have radiation with head and neck mask.
• Scheduled for 6-8 weeks of radiotherapy with 60-70Gy radiation (200cgy/fraction for 5 days/week).

Exclusion Criteria:

• patient with hodgkin lymphoma.
• Any allergy to curcumin or other condiments.