The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness

The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness

The goal of this clinical trial is to examine the effect of short-term L-Citrulline on central and peripheral blood pressure in healthy older adults. The main questions it aims to answer are:

• Does L-citrulline favorably affect blood pressure at rest and during exercise?
• Does L-citrulline favorably affect arterial stiffness?
• Does L-citrulline favorably affect muscle oxygenation at rest and during exercise?

Participants will be asked to consume L-citrulline and a placebo for six days and participate in the evaluation of their blood pressure, arterial stiffness, and muscle oxygenation before and after each intervention.

Researchers will compare L-citrulline and placebo groups to examine whether L-citrulline supplementation affects the above health parameters.

Inclusion Criteria:

• subject provides written informed consent.
• normal health profile.

Exclusion Criteria:

• history of musculoskeletal injury in the legs during the previous six months.
• smoker.
• consumption of any medication the last three months.
• consumption of any nutritional supplement the last three months.