To evaluate the activity of neovascular macula degeneretion as assessed by SD-OCTand OCT-A using a split-person study design and deep-learning quantification.

Exudative neovascular macular degeneration is the primarily an age-related retinal condition The optical coherence tomography angiography represents a novel and noninvasive diagnostic technique that allows a detailed and quantitative analysis of retinal and choriocapillary vascular features in order to choose the best therapy .

The study evaluates the changes in structural optical coherence tomography and optical coherence tomography angiography features in neovascular macular degeration patients undergoing ANTI-VEGF treatments using artificial intelligence.

Inclusion Criteria: age older than 50 years

• diagnosis of neovascular macular degeneration
• absence of previous retinal surgery and congenital eye diseases.
• absence of errors of refraction
• absence of lens opacities
• absence of low-quality OCT and OCTA images

Exclusion Criteria:• age younger than 50 years

• previous retinal surgery and congenital eye diseases
• errors of refraction
• lens opacities
• low-quality OCT and OCTA images

The participans were older than 50 years with diagnosis of neovascular macular degeneration. They did not present other ophthalmological disease