Detection of Ileoanal Pouch/Reservoir Adenomas

Detection of Ileoanal Pouch/ Reservoir Adenomas by Routine Chromoendoscopy With Indigocarmine

The detection of adenomas is the basis for the follow-up of patients with familial adenomatous polyposis, after colectomy, with a remnant rectum or an ileal pouch. The optimal method for the adenomas detection is not defined yet. Despite the proven effectiveness of indigo-carmine in different indications dye chromoendoscopy is not used in a consensual way at the international level. The situation of the ileal pouch is specific as adenomas have a usually flat shape and are much more difficult to identify than in the situation of a remnant rectum, even in the situation of > 5 mm adenomas that should be resected.

Our hypothesis is that indigo-carmine can improve adenomas detection, including > 5 mm adenomas, in patients with a an ileal pouch after colectomy improving the effectiveness of surveillance programs and potentially reducing the risk of cancer in this population.

Inclusion Criteria:

• Patients with familial adenomatous polyposis
• Ileo-anal anastomosis with pouch reservoir
• Quality of the final preparation = 3 (excellent) on the studied area
• Films made under optimal conditions for the 3 staining methods

Exclusion Criteria:

• Patient with no familial adenomatous polyposis
• Patient without Ileo-anal anastomosis reservoir
• Insufficient quality of the final preparation <3
• Absence of films made under optimal conditions for the 3 staining methods