Towards Optimal Treatment of Marfan Syndrome

Towards Optimal Treatment of Marfan Syndrome

The purpose of this study is to determine whether new magnetic resonance imaging techniques can be used as a biomarker of aortic disease severity in patients with Marfan syndrome.

Inclusion Criteria:

• MFS patients with a known FBN1 mutation
• Between 18-50 years of age

Exclusion Criteria:

• Contraindication for MR imaging
• Mental retardation
• Pregnancy, or planned pregnancy during study period

Additional exclusion criteria healthy controls:

- History of aorta disease