Metabolic Response to Food in Lung Cancer

Metabolic Response to Food in Lung Cancer

This goal of this study is to describe how unintentional weight loss influences fasting and post-prandial metabolic flexibility in participants with advanced non-small cell lung cancer.

Inclusion Criteria:

• Age greater than or equal to 18 years
• Diagnosis of non-small-cell lung cancer
• Reported weight stability or loss after cancer diagnosis
• Body mass index less than or equal to 35 kilograms per meter squared
• Ability to provide written informed consent
• Willing and able to comply with all scheduled visits, treatment plans, lab tests, and other study procedure
• Allow the collection and storage of biospecimens and data for future use

Exclusion Criteria:

• Prior diagnosis of diabetes mellitus (type 1 or type 2)
• Currently pregnant or breastfeeding
• Contraindication to consuming the liquid mixed meal
• Any medications affecting gastric motility
• Any other condition that, in the investigator's opinion, would preclude participation or successful compliance with the protocol