A Multi-country, Prospective, Post-marketing Study of UPadacitinib Evaluating Speed of Onset and Durability of Effectiveness for Patients With Moderate to Severe Crohn's Disease for 3 Years in Real-world Clinical Practice (UPlift)
A Multi-country, Prospective, Post-marketing Study of UPadacitinib Evaluating Speed of Onset and Durability of Effectiveness for Patients With Moderate to Severe Crohn's Disease for 3 Years in Real-world Clinical Practice (UPlift)
Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely active CD in real world. Speed of onset and durability of effectiveness will be assessed.
Upadacitinib is a drug approved for the treatment of CD. All study participants will receive upadacitinib as prescribed by their study doctor in accordance with approved local label. Approximately 1200 participants will be enrolled in approximately 230 sites across the world.
Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 3 years.
There is expected to be no additional burden for participants in this trial. Study visits may be conducted on-site or virtually as per standard of care.
Inclusion Criteria:
Exclusion Criteria:
Macquarie University, New South Wales 2109, Australia
Pazardzhik, Plovdiv 4400, Bulgaria
Sofiya, Sofia 1700, Bulgaria
Halifax, Nova Scotia B3H 2Y9, Canada
North York, Ontario M6A 3B4, Canada
Montreal, Quebec H4A 3J1, Canada
Beijing, Beijing Municipality 100730, China
Guangzhou, Guangdong 510655, China
St-Priest-en-Jarez, Pays de la Loire Region 42270, France
Neuilly-sur-Seine, Île-de-France Region 92200, France
Monserrato, Cagliari 09042, Italy
San Giovanni Rotondo, Foggia 71013, Italy
Monza, Monza E Brianza 20052, Italy
Rome, Roma 00168, Italy
Asahikawa-shi, Hokkaido 078-8510, Japan
Asahikawa-shi, Hokkaido 078-8510, Japan
Kyoto, Kyoto 602-8566, Japan
Hirakata-shi, Osaka 573-1191, Japan
Shimotsuke-shi, Tochigi 329-0498, Japan
Bunkyo-ku, Tokyo 113-8519, Japan
Minato-ku, Tokyo 108-8642, Japan
Mitaka-shi, Tokyo 181-8611, Japan
Shinjuku-ku, Tokyo 160-8582, Japan
Las Palmas de Gran Canaria, Las Palmas 35010, Spain