Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain

Evaluating the Effectiveness of a Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain: A Randomized Controlled Trial

To assess the effectiveness of a combined physical and psychological intervention in reducing pain and improving function in carpal tunnel syndrome patients with nociplastic pain.

Inclusion Criteria:

• Adults aged 25-65 years
• Both sexes
• Diagnosis of carpal tunnel syndrome based on clinical examination and nerve conduction studies
• Presence of nociplastic pain as determined by the Central Sensitization Inventory (CSI) with a score ≥40
• Positive tinel and phalen sign.

Exclusion Criteria:

• Previous carpal tunnel release surgery
• Other musculoskeletal or neurological disorders affecting the upper extremity