Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study aims to investigate the effectiveness of various recovery strategies (such as longer recovery periods or reduced exercise intensity) in optimizing both physical performance and overall health status. Furthermore, the study will explore the potential of using changes in blood and urinary markers as indicators for assessing recovery status.
This study will assess whether extending recovery periods between exercise sessions and reducing the volume of exercise training can enhance the recovery process and enhance performance and health-related markers, relative to a control group.
One hundred-fifth young males will be recruited to participate in a single-center, parallel-group, randomized, well-controlled, superiority trial for 8 weeks of high-volume exercise training.
A single-center, parallel-group, randomized, well-controlled, superiority trial will be conducted among 150 physically active young males. Participants will undergo an 8-week high-volume exercise during base training program, which they will be randomly assigned to one of three groups: (1) a control group, which will follow the standard exercise regimen of 35 hours/week (n = 50); (2) a less exercise volume group, which will reduce exercise volume by 15% to 30 hours/week (n = 50); and (3) an extended recovery group, which will perform the same volume of exercise as the control group (35 hours/week), but with longer recovery intervals between exercises (n = 50). The intervention will take place at the Ministry of Defense training platform.
All study measurements will be taken at baseline and throughout the study. Body composition will be assessed using multichannel bioelectrical impedance (Seca). Continuously monitor (Garmin) will be used to evaluate heart rate and heart rate variability. Fasting blood samples will be used to examine inflammatory, lipid, glycemic, and endocrine markers. Physical performance will be assessed by several validated assessments, including handgrip, maximal voluntary contraction, Wingate test, Isometric Mid-Thigh Pull (IMTP), counter movement jump (CMJ) and maximal oxygen consumption (VO2max).
The primary aim will be to determine the effect of different recovery strategies during 8 weeks of well-controlled, high-volume, large-scale, exercise training on the immune system (a), cardio-metabolic markers (b), and endocrine response (c).
Secondary aims will include: (1) To determine the effect of different recovery strategies during 8 weeks of well-controlled, high-volume, large-scale, exercise training on body strength (a), aerobic capacity (b), and body composition (c).
After baseline measurements, participants will be randomized 1:1:1 into one of three groups for 8 weeks: (1) a control group, which will follow the standard exercise regimen of 35 hours/week (n = 50); (2) a less exercise volume group, which will reduce exercise volume by 15% to 30 hours/week (n = 50); and (3) an extended recovery group, which will perform the same volume of exercise as the control group (35 hours/week), but with longer recovery intervals between exercises (n = 50).
Changes in health indices will be assessed by cardiometabolic, endocrine, and immune blood markers and body composition assessment at baseline (T0) after, 4 (T4), and 8 (T8) weeks of the intervention. Aerobic capacity, anaerobic threshold, and strength measurements will be used to determine changes in performance at T0, T4, and T8.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A regular training volume | Active Comparator | They will maintain their training volume of 35 h/week |
|
| A lower exercise volume group | Active Comparator | They will conduct 85% of the control group weekly training volume (i.e., 30h/week) |
|
| A longer rest group | Active Comparator | They will maintain the 35 h/week of exercise training, but with longer rest between exercise sessions |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| A regular training volume | Behavioral | Participate will maintain their training volume of 35 h/week |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in immune system | Tumor necrosis factor-a (pg/ml), Interleukin-6 (pg/ml) | At baseline and at 8 weeks of intervention |
| Changes in immune system | C-Reactive protein (mg/dl) | At baseline and at 8 weeks of intervention |
| Changes in cardiometabolic measurements | Glucose (mg/dl), lipid profile (total cholesterol in mg/dl, HDL in mg/dl, LDL in mg/dl) | At baseline and at 8 weeks of intervention |
| Changes in endocrine measurements | Testosterone (ng/dL) | At baseline and at 8 weeks of intervention |
| Changes in endocrine measurements | Growth hormone (ng/mL), Insulin-like growth factor 1 (ng/mL) | At baseline and at 8 weeks of intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in aerobic capacity | Wingate test (watts) | At baseline and at 8 weeks of intervention |
| Changes in aerobic capacity | Maximal O2 uptake (ml/kg/min) |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in explosive power | Countermovement jump (in cm) | At baseline and at 4 and 8 weeks of intervention |
| Strength assessment | Maximum voluntary contraction (in Newton) |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yftach Gepner, PhD | Contact | +972733804726 | gepner@tauex.tau.ac.il |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tel Aviv University | Recruiting | Tel Aviv | Other | 6997801 | Israel |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| A lower exercise volume group | Behavioral | Participate will conduct 85% of the control group weekly training volume (i.e., 30h/week) |
|
| A longer rest group | Behavioral | Participate will maintain the 35 h/week of exercise training |
|
| At baseline and at 8 weeks of intervention |
| Changes in body composition | BMI (kg/m^2) | At baseline and at 8 weeks of intervention |
| Changes in body composition | waist circumference (cm) | At baseline and at 8 weeks of intervention |
| Changes in body composition | Fat-free mass (kg) | At baseline and at 8 weeks of intervention |
| At baseline and at 4 and 8 weeks of intervention |
| Nutritional intake | protein intake (gr and in %of total kcal), carbohydrate intake (gr and in% of total kcal), fat intake (gr and in %of total kcal). | At week 2 and week 6 of intervention |
| Nutritional intake | Will be assessed by validated questionnaires such as a food diary. Macronutrients composition will be measured from the self-reported nutritional intake: daily intake (kcal) | At week 2 and week 6 of intervention |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
Not provided
Not provided