Engineering Immune Organoids to Study Pediatric Cancer

Engineering Immune Organoids to Study Pediatric Cancer (IMMUNE-ORGANOIDS)

To engineer immune organoids from pediatric patient tissues using induced-pluripotent stem cells (iPSC)

Inclusion Criteria:

• Age at diagnosis ≤ 25 years except for patients with malignant gliomas and renal tumors for whom no upper age limit is applied
• Medical suspicion or diagnosis of one of the following diseases, regardless of stage:
• Brain tumors
• Renal tumors
• Neuroblastoma
• Sarcomas
• Adult patient or parents or guardians should understand, sign and date the appropriate written informed consent from prior to any protocol-specific procedures performed. Patient should be able and willing to comply with study visits and procedures as per protocol.
• Affiliated to a social security system or beneficiary of the same.

Exclusion Criteria:

• Any histology not mentioned in the inclusion criteria
• Adult patient or parents/guardians incapable/incapable of giving its/their consent
• Patients deprived of their liberty by a judicial or administrative decision