Evaluation of PCD-CT Based Image Parameters in the Assessment and Quantification of Coronary Artery Disease

PCD-CT Registry: Evaluation of Photon Counting Detector-CT Based Image Parameters in the Assessment and Quantification of Coronary Artery Disease (EPIPHANY)

The goal of this observational study is to learn about a new type of computed tomography (Photon-Counting Detector CT) in patients with coronary artery disease.

The main questions it aims to answer are:

• How good is the image quality for the new CT
• How accurate are measurements in the images of the new CT
• Is there a relationship between measurements in the images and the management of the disease (e.g. new medication or additional investigations)
• Is there a relationship between measurements in the images and the results of follow-up investigations
• Is there a relationship between measurements in the images and the patient outcome

Participants will undergo normal clinical assessment of coronary artery disease and all data from the CT scan and additional investigations will be collected. There will be no additional investigations for the purpose of the study. After 1, 2 and 5 years, participants will be asked to answer a health questionaire.

Inclusion Criteria:

• Clinical indication for a coronary computed tomography angiography (CCTA) for the suspicion of coronary artery disease or the progression thereof
• Written informed consent

Exclusion Criteria:

• Contraindications preventing the execution of the CCTA (e.g., pregnancy)