Impact of Medications Review on Potentially Inappropriate Medications and Clinical Outcomes Among Hospitalized Older Adults

Impact of Medications Review on Potentially Inappropriate Medications and Clinical Outcomes Among Hospitalized Older Adults: A Randomized Controlled Trial (REVMED RCT) Protocol

The goal of this randomized controlled trial is to assess the effectiveness of a pharmacist-led medication review using the locally developed Malaysian Potentially Inappropriate Prescribing Screening tool in Older Adults (MALPIP), an explicit criteria in hospitalized older adults. The main questions it aims to answer are:

1. The effectiveness of the intervention in reducing the number of PIMs and chronic medications after discharge
2. The impact of the intervention on quality of life, falls events, emergency department visits, readmissions and survivals

Researchers will compare the control group to see if there is corresponding changes to the outcomes specified above.

Inclusion Criteria:

• Patients aged 60 years and above
• Taking more than five regular drugs
• Having at least one chronic medical condition
• Ability to understand and speak Malay, English, or Mandarin language

Exclusion Criteria:

• Admitted for end-of-life care
• Diagnosed with terminal illness
• Diagnosed with active cancer
• Participated in another drug trial
• Refused or unable to give consent
• Visited the Emergency Department without admission to ward
• Readmitted and have been previously enrolled in the trial