Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
So far, therapies have limited success in functional recovery in adults with chronic SCI. By introducing remote cognitive multisensory rehabilitation (CMR), which has shown significant functional improvements due to neurological recovery when delivered in-person, transformative results that (i) provide a potentially effective new therapy within the healthcare system, accessible to more patients, and (ii) demonstrate brain function changes alongside improved function in chronic SCI are anticipated. The results will inform and justify a large scale federally funded clinical trial.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Remote CMR | Experimental | adults with SCI without restriction for race, sex or socio-economic status randomized to CMR intervention. |
|
| Remote exercises | Placebo Comparator | adults with SCI without restriction for race, sex or socio-economic status randomized to remote exercise intervention. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Remote CMR | Behavioral | 12 weeks of remote CMR is done 3x/week, 45 min/session. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) Neurologic Exam | a clinical test originally designed to describe the extent and severity of a patient's SCI/D | baseline |
| International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) Neurologic Exam | a clinical test originally designed to describe the extent and severity of a patient's SCI/D | 12 weeks |
| the Neuromuscular Recovery Scale (NRS) | includes 11 items focused on the capacity of the trunk and lower extremity muscles to perform tasks such as sit, trunk extension, sit to stand, walking, and step retraining. The NRS provides a functional recovery measure that focuses on non-compensatory recovery. | baseline |
| the Neuromuscular Recovery Scale (NRS) | includes 11 items focused on the capacity of the trunk and lower extremity muscles to perform tasks such as sit, trunk extension, sit to stand, walking, and step retraining. The NRS provides a functional recovery measure that focuses on non-compensatory recovery. | 12 weeks |
| The SCI-FI/AT | (32 items) reliably measures function in the domains of basic mobility, self-care, fine motor function, and ambulation. | baseline |
| The SCI-FI/AT | (32 items) reliably measures function in the domains of basic mobility, self-care, fine motor function, and ambulation. | 12 weeks |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Minneapolis | Minnesota | 55455 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42326828 | Derived | Van de Winckel A, Herrmann AA, Carpentier ST, Bottale S, Lopez RL, Rapacz AD, Larson SJ, Deng W, Zhang L, Hendrickson TJ, Mueller BA, Nourian R, Morse LR, Lim KO. Sensorimotor recovery and neuropathic pain reduction after remotely delivered cognitive multisensory rehabilitation or remotely delivered exercise in adults with spinal cord injury: a pilot clinical trial. medRxiv [Preprint]. 2026 Jun 9:2026.06.02.26354574. doi: 10.64898/2026.06.02.26354574. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| D013118 | Spinal Cord Diseases |
| ID | Term |
|---|---|
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Remote Exercise |
| Behavioral |
12 weeks of remote exercise is done 3x/week, 45 min/session. |
|