Pulmonary Artery Denervation in Patients With Atrial Fibrillation and Group 2 of Pulmonary Hypertension

Pulmonary Artery Denervation+ Atrial Fibrillation Ablation vs Atrial Fibrillation Ablation Only in Patients With Atrial Fibrillation and Group 2 of Pulmonary Hypertension

The goal of the study is to compare efficacy and safety of the pulmonary artery denervation procedure combined with atrial fibrillation ablation versus atrial fibrillation ablation alone in patients with paroxysmal and persistent atrial fibrillation and group 2 of the pulmonary hypertension

Inclusion Criteria:

• Mean pulmonary artery pressure > 25 mm Hg and pulmonary artery wedge pressure > 15 mm Hg by right heart catheterization
• Paroxysmal or persistent atrial fibrillation
• NYHA II-III
• BNP > 105 pg/ml
• Indications for catheter ablation of atrial fibrillation according guidelines
• LVEF > 50%

Exclusion Criteria:

• Group 1,3,4 of the pulmonary hypertension
• Left atrium diameter > 6 cm
• Planned open heart surgery procedure
• Previous heart valve surgery
• Severe aortic, pulmonary, tricuspid or mitral, valves regurgitation
• Thrombus in the left heart chambers