Evaluation of the Effects of Bicarbonate-calcium Water in Premenopausal and Postmenopausal Women as a Prevention of Osteoporosis

Evaluation of the Effects of Bicarbonate-calcium Water in Premenopausal and Postmenopausal Women as a Prevention of Osteoporosis

The goal of this clinical trial is to evaluate the effect of bicarbonate-calcium water for the prevention of osteoporosis. Participants are women in pre- or post- menopausal state. The intervention group must drink bicarbonate-calcium water while the control group low mineral water

Inclusion Criteria:

• Premenopausal women aged ≥40 years
• Menopausal women, period of early menopause 1-10 years

Exclusion Criteria:

• Inclusion in other study protocols
• estrogen-replacement hormone therapy
• osteoporosis therapy
• corticosteroid therapy
• insulin therapy.
• calcium supplementation
• kidney diseases of medium-severe level
• liver diseases of medium-severe level
• severe osteoporosis