Leucine-enriched Formulas in Patients With Tumor-induced Sarcopenia

Standard Hypercaloric, Hyperproteic vs Leucine-enriched Oral Supplements in Patients With Cancer-induced Sarcopenia

Currently there is a lack of evidence for recommending specific oral supplements (OS) for nutritional support in patients with cancer, including leucine-enriched supplements.

Appropriate clinical trials that compare anthropometric and biochemical changes in nutritional parameters and clinical outcomes in patients with cancer-induced sarcopenia are required

Inclusion Criteria:

• patients of both sexes, age > 18 y-old
• cancer of different origin treated with systemic treatment chemo, radiotherapy or combination treatment t
• weight loss >5% during the previous three months or >10% during the previous six months

Exclusion Criteria:

• end-stage kidney disease
• life expectancy < 2 weeks