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The goal of this observational study is to learn more about the effect a pregnancy and delivery has on the function of the anal musculature.We will compare women who had a new delivery after suffering a severe tear in the anal musculature in their first pregnancy, with women who had two or more vaginal deliveries, but did not suffer such an injury.
The main questions we want to answer is:
Participants will be asked to complete an electronic questionnaire with information regarding their pregnancies, deliveries and potential symptoms from anal incontinence, urinary incontinence and sexual dysfunction.
Researchers will compare these two groups to find out if a new vaginal delivery has a negative effect on the function of the anal musculature.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sphincter damage | Women who suffered an injury to anal sphincter after a vaginal delivery and had a subsequent delivery after this injury |
| |
| Controls | Women who have had a at least two vaginal deliveries without suffering an injury to the anal sphincter |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Obstetric Anal Sphincter Injury | Other | We will investigate if a new vaginal delivery in those with a previous obstetric anal sphincter injury affects the function of anal musculature negatively |
| Measure | Description | Time Frame |
|---|---|---|
| The long-term impact of a new vaginal delivery on anal sphincter function in women with previous obstetric anal sphincter injury. | Number of participants with previous OASI who had a new vaginal delivery will be compared to participants with similar parity, without previous OASI. Differences in anal incontinence symptom score and quality of life will be measured by study questionnaires (St. Marks score, PFDI-20 and PFIQ-7). | 5- 20 years |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of urinary incontinence among women with previous OASI compared to women with similar parity without obstetric anal sphincter injury | Number of participants who report complaints about urinary incontinence, measured by study questionnaires (PFIQ-7, NFIR, PFDI-20). | 5-20 years |
| The risk of long- term dyspareunia and sexual dysfunction after previous obstetric anal sphincter injury compared to women with similar parity without obstetric anal sphincter injury. |
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Inclusion Criteria:
Exclusion Criteria:
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Study population will be women who had two or more vaginal deliveries at Oslo Universitetssykehus in the time period 2002-2018.
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| Name | Affiliation | Role |
|---|---|---|
| Kristine A Kilaas, M.D | Oslo University Hospital | Study Director |
| Rune Svenningsen, Ph.D | Oslo University Hospital | Study Director |
| Sissel Oversand | Oslo University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oslo University Hospital | Oslo | 0464 | Norway |
The participant data will only be available to the researchers in charge of this project
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| ID | Term |
|---|---|
| D004688 | Encopresis |
| D014549 | Urinary Incontinence |
| D012735 | Sexual Dysfunction, Physiological |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001526 | Behavioral Symptoms |
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Number of participants who report complaints about sexual dysfunction, the degree and type og dysfunction will be measured by study questionnaires (PISQ-12) |
| 5-20 years |
| D001519 | Behavior |
| D019960 | Elimination Disorders |
| D001523 | Mental Disorders |
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D000091662 | Genital Diseases |