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| ID | Type | Description | Link |
|---|---|---|---|
| 2023-A00196-39 | Other Identifier | ID-RCB |
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Portal vein pulsatility index is a marker of venous congestion evaluated by point of care ultrasound. It is associated with acute kidney injury, especially in critically ill patients. It may be considered as a dynamic marker. The investigators hypothesized that portal vein pulsatility index is higher after a fluid challenge only in patient without preload dependence in critically ill patients with cardiovascular insufficiency.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cohort | Population: Critically ill patient with:
Protocol: Administration of a fluid challenge (4mL/kg of Ringer Lactate) over 5 to 10 min. Point of care ultrasound evaluation of portal vein pulsatility index and Vexus criteria before and after the fluid challenge ; fluid challenge induced cardiac index variations estimated by pulse contour analysis |
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| Measure | Description | Time Frame |
|---|---|---|
| Portal vein pulsatility index variation induced by the fluid challenge (%), defined by: Portal vein pulsatility index before the fluid challenge - portal vein pulsatility index after the fluid challenge. | Portal vein pulsatility index is defined as the (maximal velocity - minimal velocity) / maximal velocity assessed with doppler in portal vein estimated with point of care ultrasound. | One hour |
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Inclusion Criteria:
vasopressor requirement to maintain mean arterial pressure >65mmHg AND
at least one of the following criteria:
Exclusion Criteria:
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Adult intensive care patients with both grade 1 or higher venous congestion (VeXus C criteria) and acute circulatory failure.
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| Name | Affiliation | Role |
|---|---|---|
| Martin RUSTE, MD | Département d'anesthésie-réanimation | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital cardiologique Louis Pradel | Bron | 69500 | France |
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| ID | Term |
|---|---|
| D006940 | Hyperemia |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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