Sonography-Guided Volumetric Rejuvenation on Dorsal Hands

Sonography-Guided Volumetric Rejuvenation on Dorsal Hands: A Split-Hand Randomized Controlled Trial

The goal of this randomized controlled study is to guide volumetric rejuvenation on dorsal hands with the maximal aesthetic appearance. The main questions it aims to answer are:

• Which fatty layer(s) is/are the most suitable for filler injection?
• Is it feasible to make precise filler injections with sonography guidance? Participants will receive sonography-guided injection on the one hand and another with blinded injection.

In our previous study, volumetric fat loss was noted in the 3 fatty laminae of dorsal hands during aging; the dorsal intermediate lamina (DIL) showed the greatest progressive fat loss after the age of 30. Volumetric rejuvenation of the 3 laminae may result in the most aesthetic appearance, especially in women. It is necessary to develop precise rejuvenation therapies according to the aging process of the dorsum of the hands that will yield the most aesthetic appearance.

Inclusion Criteria:

• Diagnosis of aging changes on the dorsal hands
• Aged ≥18 years

Exclusion Criteria:

• History of severe hand dermatitis
• History of rheumatic arthritis
• History of major hand trauma
• History of limb edema
• History of recent significant weight changes
• History of previous filler injection to the dorsal hands
• History of intravenous catheter insertion and hemodialysis via the forearms or hands