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The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2). An accurate SpO2 value is essential for optimal management of the O2 flow delivered to patients. Several factors can influence this measurement and the choice of ventilatory support: the type of oximeter used, skin pigmentation and the oxygenation goal.
The objective of our study is to evaluate the impact of the oxygenation goal and the oximeter used on oxygen flows in patients with COPD (or with hypercapnia, or at risk of hypercapnia) and in patients without COPD (in particular pneumonia, pulmonary fibrosis and other pathologies) Our hypothesis is that the SpO2 target and oximeter used will have an impact on oxygen flows and that these effects will be synergistic in these different populations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 88% SpO2 target | Experimental | During this periods , oxygen will be administered in manual titration to reach 88% of SpO2. |
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| 90% SpO2 target | Experimental | During this periods , oxygen will be administered in manual titration to reach 90% of SpO2. |
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| 92% SpO2 target | Experimental | During this periods , oxygen will be administered in manual titration to reach 92% of SpO2. |
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| 94% SpO2 target | Experimental | During this periods , oxygen will be administered in manual titration to reach 94% of SpO2. |
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| 96% SpO2 target | Experimental | During this periods , oxygen will be administered in manual titration to reach 96% of SpO2. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Masimo oximeter | Device | During this period, the Masimo oximeter Radical 7 was used for SpO2 reading |
|
| Measure | Description | Time Frame |
|---|---|---|
| Oxygen flow | the mean oxygen flow to reach the SpO2 target +/- 1% during 2 minutes for each period and each oximeter | assessed up to 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Partial oxygen weaning | Rate of partial oxygen weaning (Oxygen flow <=0.5 L/min) to reach the SpO2 target for each period and each oximeter | assessed up to 10 minutes - until SpO2 target stability for 2 minutes |
| Complete oxygen weaning |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut Universitaire de Cardiologie et de Pneumologie de Québec | Québec | Quebec | G1V4G5 | Canada |
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| Nellcor oximeter | Device | During this period, the Nellcor oximeter N-600 was used for SpO2 reading |
|
| Nonin oximeter | Device | During this period, the Nonin oximeter was used for SpO2 reading |
|
Rate of complete oxygen weaning (Oxygen flow <=0.1 L/min) to reach the SpO2 target for each period and each oximeter
| assessed up to 10 minutes - until SpO2 target stability for 2 minutes |
| High oxygen flow | Rate of high oxygen flow (Oxygen flow >5.0 L/min) to reach the SpO2 target for each period and each oximeter | assessed up to 10 minutes - until SpO2 target stability for 2 minutes |
| Oximeter bias comparison | the mean bias between the result of the different oximeter | assessed up to 10 minutes - until SpO2 target stability for 2 minutes |
| ID | Term |
|---|---|
| D011014 | Pneumonia |
| D000860 | Hypoxia |
| D012120 | Respiration Disorders |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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