This observational study aims to investigate the relationship between public health and the skin microbiome in the province of Zhejiang. Due to the lack of current research on the skin microbiome, the following general questions will be investigated in this study: 1) What connection exists between dietary practices and facial skin microbiome? 2) How do people's lifestyle routines affect the facial skin microbiome? 3) What effects does the altered living environment have on people's facial skin microbiomes? 4) How do the seasons affect people's facial skin microbiomes?

Every 3 to 4 months, the participants' facial skin microbiota samples will be taken, and they will be asked to complete a survey.

Inclusion Criteria:

• ages from 10+.

Exclusion Criteria:

• a severe medical history, including a history of surgery or medication, or serious illnesses such as cancer, liver disease, kidney disease, or craniocerebral trauma.
• recent medical treatment (topical antibiotics, corticosteroids, and other anti-inflammatory drugs within 4 weeks, and systemic antibiotics, corticosteroids, and other immunosuppressive drugs within 6 months)

The population of this study will be selected from people that reside in Zhejiang province, and they should fulfill the eligibility criteria.