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Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma
All patients were subclassified into either the hemodynamic stability group (HS group) or the hemodynamic instability group (HU group) according to whether intraoperative hemodynamic instability occurred. Differences in data between the two groups were examined, and the risk factors for intraoperative hemodynamic instability were analyzed using logistic regression.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PXB combined with venous dilation group | No Intervention | Use of PXB combined with intravenous volume expansion during preoperative preparation in patients with pheochromocytoma | |
| PXB group | Experimental | PXB alone during preoperative preparation in patients with pheochromocytoma |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma | Drug | Abandonment of intravenous volume expansion with alpha-blockers during preoperative preparation in patients with pheochromocytoma |
| Measure | Description | Time Frame |
|---|---|---|
| intraoperative mean arterial pressure | an intraoperative mean arterial pressure <60 mmHg is considered to be hemodynamically unstable | During surgery |
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Inclusion Criteria:
Clinical diagnosis of adrenal pheochromocytoma Must be able to swallow tablets
Exclusion Criteria:
Bilateral or multiple pheochromocytomas. Ectopic pheochromocytoma
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| Name | Affiliation | Role |
|---|---|---|
| kunwu yan, Master | Handan First Hospital | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33575936 | Background | Meijs AC, Snel M, Corssmit EPM. Pheochromocytoma/paraganglioma crisis: case series from a tertiary referral center for pheochromocytomas and paragangliomas. Hormones (Athens). 2021 Jun;20(2):395-403. doi: 10.1007/s42000-021-00274-6. Epub 2021 Feb 11. | |
| 27696513 | Background | Challis BG, Casey RT, Simpson HL, Gurnell M. Is there an optimal preoperative management strategy for phaeochromocytoma/paraganglioma? Clin Endocrinol (Oxf). 2017 Feb;86(2):163-167. doi: 10.1111/cen.13252. Epub 2016 Oct 24. |
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| ID | Term |
|---|---|
| D010673 | Pheochromocytoma |
| ID | Term |
|---|---|
| D010235 | Paraganglioma |
| D018358 | Neuroendocrine Tumors |
| D017599 | Neuroectodermal Tumors |
| D009373 | Neoplasms, Germ Cell and Embryonal |
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| 27561909 | Background | Randle RW, Balentine CJ, Pitt SC, Schneider DF, Sippel RS. Selective Versus Non-selective alpha-Blockade Prior to Laparoscopic Adrenalectomy for Pheochromocytoma. Ann Surg Oncol. 2017 Jan;24(1):244-250. doi: 10.1245/s10434-016-5514-7. Epub 2016 Aug 25. |
| 36010839 | Background | Bihain F, Nomine-Criqui C, Guerci P, Gasman S, Klein M, Brunaud L. Management of Patients with Treatment of Pheochromocytoma: A Critical Appraisal. Cancers (Basel). 2022 Aug 9;14(16):3845. doi: 10.3390/cancers14163845. |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D009380 | Neoplasms, Nerve Tissue |