Inulin Supplementation in Patients With Type 1 Diabetes

Efficacy Evaluation of Inulin Supplementation on Metabolic Control and Akkermansia Muciniphila Levels in Patients With Type 1 Diabetes: a Pilot Study

The aim of this study is to compare the glycemic and metabolic control of type 1 diabetic patients in replacement therapy with insulin, comparing those treated with a supplementation of prebiotics (inulin) and those treated with a placebo.

Therefore, the primary objective of the study is represented by the proportion of patients with better glycemic control (basal and post-prandial euglycemia time) and optimal metabolic control (HbA1c, lipid profile, C-RP).

Inclusion Criteria:

• Patients with T1D, diagnosed before 35 years of age will be enrolled

Exclusion Criteria:

• advanced complications of T1D (established renal failure, severe retinopathy and diabetic neuropathy)
• BMI> 30 kg / m2.