A Prospective Observational Study for Evaluation of Safety and Effectiveness of Rinvoq in Moderately to Severely Active Ulcerative Colitis; a Japanese Post-Marketing Study
A Prospective Observational Study for Evaluation of Safety and Effectiveness of Rinvoq in Moderately to Severely Active Ulcerative Colitis; a Japanese Post-Marketing Study
Ulcerative colitis (UC) is an idiopathic, chronic, inflammatory disease affecting the colon. Participants with UC have mucosal inflammation starting in the rectum that can extend continuously to proximal segments of the colon. This study will assess how safe and effective Rinvoq is in treating adult participants with moderate to severe ulcerative colitis (UC). Adverse events and change in disease activity will be assessed.
Rinvoq is a drug approved for the treatment of ulcerative colitis (UC). All study participants will receive Rinvoq as prescribed by their study doctor in accordance with approved local label. Approximately 300 adult participants will be enrolled in Japan.
Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 60 weeks.
There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
Inclusion Criteria:
Exclusion Criteria:
Anjo-shi, Aichi-ken 446-8602, Japan
Ichinomiya-shi, Aichi-ken 494-0001, Japan
Niwa-gun, Aichi-ken 480-0147, Japan
Toyota-shi, Aichi-ken 470-1219, Japan
Hachinohe-shi, Aomori 031-8555, Japan
Inzai-shi, Chiba 270-1613, Japan
Kashiwa-shi, Chiba 277-0871, Japan
Chikugo-shi, Fukuoka 833-0005, Japan
Kitakyusyu-shi, Fukuoka 803-0836, Japan
Kurume-shi, Fukuoka 839-0809, Japan
Koriyama-shi, Fukushima 963-8501, Japan
Ogaki-shi, Gifu 503-0031, Japan
Seki-shi, Gifu 501-3802, Japan
Tajimi-shi, Gifu 507-8522, Japan
Takasaki-shi, Gunma 370-0848, Japan
Fukuyama-shi, Hiroshima 720-8520, Japan
Nishinomiya-shi, Hyōgo 662-0973, Japan
Nishinomiya-shi, Hyōgo 663-8501, Japan
Inashiki-shi, Ibaraki 300-0332, Japan
Tsuchiura-shi, Ibaraki 300-0053, Japan
Atsugi-shi, Kanagawa 243-0018, Japan
Kamakura-shi, Kanagawa 247-0056, Japan
Kawasaki-shi, Kanagawa 215-0026, Japan
Sagamihara-shi, Kanagawa 252-0375, Japan
Yokkaichi-shi, Mie-ken 510-0016, Japan
Komagane-shi, Nagano 3994117, Japan
Nagaoka-shi, Niigata 940-2085, Japan
Ginowan-shi, Okinawa 901-2725, Japan
Okinawa-shi, Okinawa 904-2195, Japan
Fujidera-shi, Osaka 583-0027, Japan
Hirakata-shi, Osaka 573-1191, Japan
Sakai-shi, Osaka 591-8025, Japan
Toyonaka-shi, Osaka 560-0055, Japan
Ageo-shi, Saitama 362-0075, Japan
Kumagaya-shi, Saitama 331-0074, Japan
Sunto-gun, Shizuoka 411-8611, Japan
Bunkyo-ku, Tokyo 113-8431, Japan
Chuo-ku, Tokyo 104-0061, Japan
Koganei-shi, Tokyo 184-0004, Japan
Minato-ku, Tokyo 108-8642, Japan
Mitaka-shi, Tokyo 181-8611, Japan
Setagaya-ku, Tokyo 155-0032, Japan
Shibuya-ku, Tokyo 151-0053, Japan
Shinagawa-ku, Tokyo 142-8666, Japan
Shinjuku-ku, Tokyo 160-0023, Japan
Shinjuku-ku, Tokyo 160-8582, Japan
Shinjuku-ku, Tokyo 162-8666, Japan
Shinjuku-ku, Tokyo 169-0073, Japan